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Publications

2012
Cao S, Cryan L, Habeshian KA, Murillo C, Tamayo-Castillo G, Rogers MS, Clardy J. Phenolic compounds as antiangiogenic CMG2 inhibitors from Costa Rican endophytic fungi [Internet]. 2012; Bioorg Med Chem Lett. Sep 15;22(18):5885-8.
Jasuja R, Passam FH, Kennedy DR, Kim SH, Hessem VL, Lin L, Bowley SR, Joshi SS, Dilks JR, Furie B, Furie BC, Flaumenhaft R. Protein disulfide isomerase inhibitors constitute a new class of antithrombotic agents [Internet]. 2012; J Clin Invest 122, 2104-13.
Haggerty TJ, Dunn IS, Rose LB, Newton EE, Kurnick JT. A screening assay to identify agents that enhance T-cell recognition of human melanomas [Internet]. 2012; Assay and drug development technologies 10, 187-201.
Jo H, Mondal S, Tan D, Nagata E, Takizawa S, Sharma AK, Hou Q, Shanmugasundaram K, Prasad A, Tung JK, Tejeda AO, Man H, Rigby AC, Luo HR. Small molecule-induced cytosolic activation of protein kinase Akt rescues ischemia-elicited neuronal death [Internet]. 2012; Proceedings of the National Academy of Sciences of the United States of America 109, 10581-6
Ciustea M, Mootien S, Rosato AE, Perez O, Cirillo P, Yeung KR, Ledizet M, Cynamon MH, Aristoff PA, Koski RA, Kaplan PA, Anthony KG. Thiadiazolidinones: a new class of alanine racemase inhibitors with antimicrobial activity against methicillin-resistant Staphylococcus aureus [Internet]. 2012; Biochem Pharmacol 83(3):368-77.
Sigoillot FD, Lyman S, Huckins JF, Adamson B, Chung E, Quattrochi B, King RW. A bioinformatics method identifies prominent off-targeted transcripts in RNAi screens. 2012;Feb 19; 9(4):363-6.
Zhao H, Lin W, Kumthip K, Cheng D, Fusco DN, Hofmann O, Jilg N, Tai AW, Goto K, Zhang L, Hide W, Jang JY, Peng LF, Chung RT. A functional genomic screen reveals novel host genes that mediate interferon-alpha’s effects against hepatitis C virus. J Hepatol 2012;56(2):326-33.
Zhang X, Bedigian AV, Wang W, Eggert US. G protein-coupled receptors participate in cytokinesis [Internet]. 2012; Cytoskeleton (Hoboken, N.J.) 69, 810-8.
Adamson B, Smogorzewska A, Sigoillot FD, King RW, Elledge SJ. A genome-wide homologous recombination screen identifies the RNA-binding protein RBMX as a component of the DNA-damage response. Nat Cell Biol 2012;14(3):318-28.
Papageorgiou A, Avruch J. A genome-wide RNAi screen for polypeptides that alter rpS6 phosphorylation. Methods Mol Biol 2012;821:187-214.
Gewurz BE, Towfic F, Mar JC, Shinners NP, Takasaki K, Zhao B, Cahir-McFarland ED, Quackenbush J, Xavier RJ, Kieff E. Genome-wide siRNA screen for mediators of NF-κB activation. Proc Natl Acad Sci USA 2012;Feb 14; 109(7):2467-72.
Jurak I, Silverstein LB, Sharma M, Coen DM. Herpes simplex virus is equipped with RNA- and protein-based mechanisms to repress expression of ATRX, an effector of intrinsic immunity. J Virol 2012;Sep; 86(18):10093-102.
2011
Cotta-Ramusino C, 3rd ERMD, Hurov K, Sowa ME, Harper JW, Elledge SJ. A DNA damage response screen identifies RHINO, a 9-1-1 and TopBP1 interacting protein required for ATR signaling. Science 2011;332(6035):1313-7.
Sigoiloot FD, King RW. Vigilance and Validation: Keys to Success in RNAi Screening. ACS Chem Biol 2011;6(1):47-60.
Senapedis WT, Kennedy CJ, Boyle PM, Silver PA. Whole genome siRNA cell-based screen links mitochondria to Akt signaling network through uncoupling of electron transport chain. Mol Biol Cell 2011;22(10):1791-805.
Thorne CA, Lafleur B, Lewis M, Hanson AJ, Jernigan KK, Weaver DC, Huppert KA, Chen TW, Wiehaidit C, Cselenyi CS, Tahinci E, Meyers KC, Waskow E, Orton D, Salic A, Lee LA, Robbins DJ, Huppert SS, Lee E. A biochemical screen fro identification of small molecule regulators of the Wnt pathway using Xenopus egg extracts. J Biomol Screen 2011;16(9):995-1006.
Li X, Liu N, Zhang H, Knudson SE, Li HJ, Lai CT, Simmerling C, Slayden RA, Tonge PJ. CoA adducts of 4-oxo-4-phenylbut-2-enoates: inhibitors of MenB from the M. tuberculosis menaquinone biosynthesis pathway [Internet]. 2011; ACS Med Chem Lett 2(11):818-823

Data from this screen has been deposited in PubChem Bioassay. AID #540299

Huh JR, Leung MW, Huang P, Ryan DA, Krout MR, Malapaka RR, Chow J, Manel N, Ciofani M, Kim SV, Cuesta A, Santori FR, Lafaille JJ, Xu HE, Gin DY, Rastinejad F, Littman DR. Digoxin and its derivatives suppress TH17 cell differentiation by antagonizing RORγt activity [Internet]. 2011; Nature 472, 486-90
Kawahara G, Karpf JA, Myers JA, Alexander MS, Guyon JR, Kunkel LM. Drug screening in a zebrafish model of Duchenne muscular dystrophy [Internet]. 2011; Proc Natl Acad Sci U S A 108:5331-6.
Schulte J, Sepp KJ, Wu C, Hong P, Littleton JT. High-content chemical and RNAi screens for suppressors of neurotoxicity in a Huntington’s Disease model [Internet]. 2011; PLoS One 6(8): e23841

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