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Publications

2011
Geiss BJ, Stahla-Beek HJ, Hannah AM, Gari HH, Henderson BR, Saeedi BJ, Keenan SM. A high-throughput screening assay for the identification of flavivirus NS5 capping enzyme GTP-binding inhibitors: implications for antiviral drug development [Internet]. 2011; J Biomol Screen 16(8):852-61
Campagnola G, Gong P, Peersen OB. High-throughput screening identification of poliovirus RNA-dependent RNA polymerase inhibitors [Internet]. 2011; Antiviral Res 91(3):241-251

Data from this screen has been deposited in PubChem Bioassay. AID #588519

Faghiri Z, Santiago RB, Wu Z, Widmer G. High-throughput screening in suboptimal growth conditions identifies agonists of Giardia lamblia proliferation [Internet]. 2011; Parasitology Feb;138(2):194-200
Schormann N, Sommers CI, Prichard MN, Keith KA, Noah JW, Nuth M, Ricciardi RP, Chattopadhyay D. Identification of protein-protein interaction inhibitors targeting vaccinia virus processivity factor for developing antiviral agents [Internet]. 2011; Antimicrob Agents Chemother 55(11):5054-62.
Zhou Y, Rajabi H, Kufe D. Mucin 1 C-terminal subunit oncoprotein is a target for small-molecule inhibitors [Internet]. 2011; Mol Pharmacol 79(5):886-93.
Anthony KG, Strych U, Yeung KR, Shoen CS, Perez O, Krause KL, Cynamon MH, Aristoff PA, Koski RA. New classes of alanine racemase inhibitors identified by high-throughput screening show antimicrobial activity against Mycobacterium tuberculosis [Internet]. 2011; PLoS One 6(5):e20374
Greenberger S, Yuan S, Walsh LA, Boscolo E, Kang KT, Matthews B, Mulliken JB, Bischoff J. Rapamycin suppresses self-renewal and vasculogenic potential of stem cells isolated from infantile hemangioma [Internet]. 2011; J Invest Dermatol Dec;131(12):2467-76.
Gonsalves F, Klein K, Carson B, Katz S, Ekas L, Evans S, Nagourney R, Cardozo T, Brown AMC, Dasgupta R. An RNAi-based chemical genetic screen identifies three small-molecule inhibitors of the Wnt/wingless signaling pathway. Proc Natl Acad Sci USA 2011;108(15):5954-63.
Côté M, Misasi J, Ren T, Bruchez A, Lee K, Filone CM, Hensley L, Li Q, Ory D, Chandran K, Cunningham J. Small molecule inhibitors reveal Niemann-Pick C1 is essential for Ebola virus infection [Internet]. 2011; Nature 477(7364):344-8
Sun F, Zhou L, Zhao BC, Deng X, Cho H, Yi C, Jian X, Song CX, Luan CH, Bae T, Li Z, He C. Targeting MgrA-mediated virulence regulation in Staphylococcus aureus [Internet]. 2011; Chem Biol 18:1032-41.

Data from this screen has been deposited in PubChem Bioassay. AID #602314

Harris ES, Erickson SD, Tolopko AN, Cao S, Craycroft JA, Scholten R, Fu Y, Wang W, Liu Y, Zhao Z, Clardy J, Shamu CE, Eisenberg DM. Traditional Medicine Collection Tracking System (TM-CTS): a database for ethnobotanically driven drug-discovery programs. J Ethnopharmacol 2011;135(2):590-3.
Sigoillot FD, King RW. Vigilance and Validation: Keys to Success in RNAi Screening. ACS Chem Biol 2011;6(1):47-60.
Kepp O, Galluzi L, Lipinski M, Yuan J, Kroemer G. Cell death assays for drug discovery. Nat Rev Drug Discov 2011;10(3):221-37.
2010
Moore MJ, Wang Q, Kennedy CJ, Silver PA. An alternative splicing network links cell-cycle control to apoptosis. Cell 2010;142(4):625-36.
Lipinski MM, Zheng B, Lu T, Yan Z, Py BF, Ng A, Xavier RJ, Li C, Yankner BA, Scherzer CR, Yuan J. Genome-wide analysis reveals mechanisms modulating autophagy in normal brain aging and in Alzheimer’s disease. Proc Natl Acad Sci USA. 2010;107(32):14164-9.
Smith JA, White EA, Sowa ME, Powell MLC, Ottinger M, Harper JW, Howley PM. Genome-wide siRNA screen identifies SMCX, EP400, and Brd4 as E2-dependent regulators of human papillomavirus oncogene expression. Proc Natl Acad Sci USA. 2010;107(8):3752-7.
Yoon JC, Ng A, Kim BH, Bianco A, Xavier RJ, Elledge SJ. Wnt signaling regulates mitochondrial physiology and insulin sensitivity. Genes Dev 2010;24(14):1507-18.
Kwan P, Birmingham A. NoiseMaker: simulated screens for statistical assessment. Bioinformatics 2010;26(19):2484-5.
Paik EJ, de Jong JL, Pugach E, Opara P, Zon L. A chemical genetic screen in zebrafish for pathways interacting with cdx4 in primitive hematopoiesis [Internet]. http://www.ncbi.nlm.nih.gov/pubmed?cmd=Search&term=20415644%5BPMID%5D 2010; Zebrafish 7, 61-8
Lee K, Campbell J, Swoboda JG, Cuny GD, Walker S. Development of improved inhibitors of wall teichoic acid biosynthesis with potent activity against Staphylococcus aureus [Internet]. 2010; Bioorg Med Chem Lett 20(5):1767-70

Data from this screen has been deposited in PubChem Bioassay. AID #463173

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