Publications by Year: 2018

2018
Bodnar NO, Kim KH, Ji Z, Wales TE, Svetlov V, Nudler E, Engen JR, Walz T, Rapoport TA. Structure of the Cdc48 ATPase with its ubiquitin-binding cofactor Ufd1-Npl4. Nat Struct Mol Biol 2018;25(7):616-622.
Takahashi N, Chen H-Y, Harris IS, Stover DG, Selfors LM, Bronson RT, Deraedt T, Cichowski K, Welm AL, Mori Y, Mills GB, Brugge JS. Cancer Cells Co-opt the Neuronal Redox-Sensing Channel TRPA1 to Promote Oxidative-Stress Tolerance [Internet]. Cancer Cell 2018;33(6):985-1003. Publisher's Version
Eubanks AL, Perkins MM, Sylvester K, Ganley JG, Posfai D, Sanschargrin PC, Hong J, Sliz P, Derbyshire ER. In silico Screening and Evaluation of Plasmodium falciparum Protein Kinase 5 (PK5) Inhibitors. ChemMedChem 2018;13(23):2479-2483.
Buss JA, Baidin V, Welsh MA, Flores-Kim J, Cho H, Wood BM, Uehara T, Walker S, Kahne D, Bernhardt TG. Pathway-Directed Screen for Inhibitors of the Bacterial Cell Elongation Machinery [Internet]. Antimicrob Agents Chemother 2018;63(1)::e01530-18. Publisher's Version
Serafini PR, Feyder MJ, Hightower RM, Garcia-Perez D, Vieira NM, Lek A, Gibbs DE, Moukha-Chafiq O, Augelli-Szafran CE, Kawahara G, Widrick JJ, Kunkel LM, Alexander MS. A limb-girdle muscular dystrophy 2I model of muscular dystrophy identifies corrective drug compounds for dystroglycanopathies [Internet]. JCI Insight 2018;3(18):e120493. Publisher's Version
Lian W, Jang J, Potisopon S, Li P-C, Rahmeh A, Wang J, Kwiatkowski NP, Gray NS, Yang PL. Discovery of Immunologically Inspired Small Molecules That Target the Viral Envelope Protein. ACS Infect Dis 2018;4(9):1395-1406.
Vincent BM, Tardiff DF, Piotrowski JS, Aron R, Lucas MC, Chung CY, Bacherman H, Chen YQ, Pires M, Subramaniam R, Doshi DB, Sadlish H, Raja WK, Solís EJ, Khurana V, Bourdonnec BL, Scannevin RH, Rhodes KJ. Inhibiting Stearoyl-CoA Desaturase Ameliorates α-Synuclein Cytotoxicity [Internet]. Cell Rep 2018;25(10):2742-2754. Publisher's Version
Pishchany G, Mevers E, Ndousse-Fetter S, Horvath DJ, Paludo CR, Silva-Junior EA, Koren S, Skaar EP, Clardy J, Kolter R. Amycomicin is a potent and specific antibiotic discovered with a targeted interaction screen [Internet]. Proc Natl Acad Sci 2018;115(40):10124-10129. Publisher's Version
Praveschotinunt P, Courchesne N-MD, denHartog I, Lu C, Kim JJ, Nguyen PQ, Joshi NS. Tracking of Engineered Bacteria In Vivo Using Nonstandard Amino Acid Incorporation. ACS Synth Biol 2018;7(6):1640-1650.
Yao L, Seaton SC, Ndousse-Fetter S, Adhikari AA, DiBenedetto N, Mina AI, Banks AS, Bry L, Devlin AS. A selective gut bacterial bile salt hydrolase alters host metabolism [Internet]. eLife 2018;7:e37182. Publisher's Version
Dumoulin PC, Burleigh BA. Stress-Induced Proliferation and Cell Cycle Plasticity of Intracellular Trypanosoma cruzi Amastigotes [Internet]. mBio 2018;9(4):e00673-18. Publisher's Version
Jones DS, Jenney AP, Joughin BA, Sorger PK, Lauffenburger DA. Inflammatory but not mitogenic contexts prime synovial fibroblasts for compensatory signaling responses to p38 inhibition. Sci Signal 2018;11(520)
Sridhar R, Takei H, Syed R, Kobayashi IS, Hui LB, Kamal A, Tenen DG, Kobayashi SS. Styryl Quinazolinones as Potential Inducers of Myeloid Differentiation via Upregulation of C/EBPα [Internet]. Molecules 2018;23(8) Publisher's Version
deWispelaere M, Lian W, Potisopon S, Li P-C, Jang J, Ficarro SB, Clark MJ, Zhu X, Kaplan JB, Pitts JD, Wales TE, Wang J, Engen JR, Marto JA, Gray NS, Yang PL. Inhibition of Flaviviruses by Targeting a Conserved Pocket on the Viral Envelope Protein [Internet]. Cell Chem Biol 2018;25(8):1006-1016. Publisher's Version
Sun B, Wang G, Liu H, Liu P, Twal WO, Cheung H, Carroll SL, Ethier SP, Mevers EE, Clardy J, Roberts T, Chen C, Li Q, Wang L, Yang M, Zhao JJ, Wang Q. Oridonin inhibits aberrant AKT activation in breast cancer [Internet]. Oncotarget 2018;9(35):23878-23889. Publisher's Version
Kim W, Zhu W, Hendricks GL, Van Tyne D, Steele AD, Keohane CE, Fricke N, Conery AL, Shen S, Pan W, Lee K, Rajamuthiah R, Fuchs BB, Vlahovska PM, Wuest WM, Gilmore MS, Gao H, Ausubel FM, Mylonakis E. A new class of synthetic retinoid antibiotics effective against bacterial persisters. Nature 2018;556(7699):103-107.
Liao J, Xu G, Mevers EE, Clardy J, Watnick PI. A high-throughput, whole cell assay to identify compounds active against carbapenem-resistantKlebsiella pneumoniae. PLoS ONE 2018;13(12):e0209389.
Amin P, Florez M, Najafov A, Pan H, Geng J, Ofengeim D, Dziedzic SA, Wang H, Barrett VJ, Ito Y, LaVoie MJ, Yuan J. Regulation of a distinct activated RIPK1 intermediatebridging complex I and complex II inTNFα-mediated apoptosis. PNAS 2018;115(26):E5944-E5953.
Wang L, Rowe RG, Jaimes A, Yu C, Nam Y, Pearson DS, Zhang J, Xie X, Marion W, Heffron GJ, Daley GQ, Sliz P. Small-Molecule Inhibitors Disrupt let-7 Oligouridylation and Release the Selective Blockade of let-7 Processing by LIN28. Cell Rep 2018;23(10):3091-3101.
Zhang G, Baidin V, Pahil KS, Moison E, Tomasek D, Ramadoss NS, Chatterjee AK, McNamara CW, Young TS, Schultz PG, Meredith TC, Kahne D. Cell-based screen for discovering lipopolysaccharide biogenesis inhibitors. PNAS 2018;115(26):6834-6839.

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