Publications

2018
Amin P, Florez M, Najafov A, Pan H, Geng J, Ofengeim D, Dziedzic SA, Wang H, Barrett VJ, Ito Y, LaVoie MJ, Yuan J. Regulation of a distinct activated RIPK1 intermediatebridging complex I and complex II inTNFα-mediated apoptosis. PNAS 2018;
Wang L, Rowe RG, Jaimes A, Yu C, Nam Y, Pearson DS, Zhang J, Xie X, Marion W, Heffron GJ, Daley GQ, Sliz P. Small-Molecule Inhibitors Disrupt let-7 Oligouridylation and Release the Selective Blockade of let-7 Processing by LIN28. Cell Rep 2018;23(10):3091-3101.
Zhang G, Baidin V, Pahil KS, Moison E, Tomasek D, Ramadoss NS, Chatterjee AK, McNamara CW, Young TS, Schultz PG, Meredith TC, Kahne D. Cell-based screen for discovering lipopolysaccharide biogenesis inhibitors. PNAS 2018;
Gonzalez KN, Zaganjor E, Ishikawa Y, Spinelli JB, Yoon H, Lin JR, Satterstrom FK, Ringel A, Mulei S, Souza A, Gorham JM, Benson CC, Seidman JG, Sorger PK, Clish CB, Haigis MC. Small-Molecule Screen Identifies De Novo Nucleotide Synthesis as a Vulnerability of Cells Lacking SIRT3. Cell Rep 2018;22(8):1945-1955.
Zeid R, Lawlor MA, Poon E, Reyes JM, Fulciniti M, Lopez MA, Scott TG, Nabet B, Erb MA, Winter GE, Jacobson Z, Polaski DR, Karlin KL, Hirsch RA, Munshi NP, Westbrook TF, Chesler L, Lin CY, Bradner JE. Enhancer invasion shapes MYCN-dependent transcriptional amplification in neuroblastoma. Nat Genet. 2018;Jan 29 doi: 10.1038/s41588-018-0044-9.
Ouchida AT, Li Y, Geng J, Najafov A, Ofengeim D, Sun X, Yu Q, Yuan J. Synergistic effect of a novel autophagy inhibitor and Quizartinib enhances cancer cell death. Cell Death Dis. 2018;9(2):138.
2017
Hafner M, Niepel M, Subramanian K, Sorger PK. Designing drug response experiments and quantifying their results . Curr Protoc Chem Biol 2017;9(2):96-116.
Niepel M, Hafner M, Chung M, Sorger PK. Measuring cancer drug sensitivity and resistance in cultured cells . Curr Protoc Chem Biol 2017;9(2):55-74.
Abrial M, Paffett-Lugassy N, Jeffrey S, Jordan D, O'Laughlin E, Frederick CJ, Burns CG, Burns CE. TGF-β Signaling Is Necessary and Sufficient for Pharyngeal Arch Artery Angioblast Formation. Cell Rep 2017;20(4):973-983.
Zheng H, Colvin CJ, Johnson BK, Kirchhoff PD, Wilson M, Jorgensen-Muga K, Larsen SD, Abramovitch RB. Inhibitors of Mycobacterium tuberculosis DosRST signaling and persistence. Nat Chem Biol 2017;13(2):218-225.
Coulson GB, Johnson BK, Zheng H, Colvin CJ, Fillinger RJ, Haiderer ER, Hammer ND, Abramovitch RB. Targeting Mycobacterium tuberculosis Sensitivity to Thiol Stress at Acidic pH Kills the Bacteriumand Potentiates Antibiotics. Cell Chem Biol 2017;24(8):993-1004.
Fu B, Zhao M, Wang L, Patil G, Smith JA, Juncadella IJ, Zuvela-Jelaska L, Dorf ME, Li S. RNAi Screen and Proteomics Reveal NXF1 as a Novel Regulator of IRF5 Signaling. Sci Rep 2017;Jun 2; 7(1):2683.
Strang BL. RO0504985 is an inhibitor of CMGC kinase proteins and has anti-human cytomegalovirus activity [Internet]. Antiviral Res 2017;144:21-26. Publisher's Version
Maura D, Drees SL, Bandyopadhaya A, Kitao T, Negri M, Starkey M, Lesic B, Milot S, Deziel E, Zahler R, Pucci M, Felici A, Fetzner S, Lepine F, Rahme LG. Polypharmacology Approaches against the Pseudomonas aeruginosa MvfR Regulon and Their Application in Blocking Virulence and Antibiotic Tolerance. ACS Chem Bio 2017;:[Epub ahead of print].
Simpson KJ, Smith JA. Knocking down the obstacles to functional genomics data sharing. Sci Data 2017;4:170019 doi:10.1038/sdata.2017.19.
Khan AS, Murray MJ, Ho CM, Zuercher WJ, Reeves MB, Strang BL. High Throughput Screening of a GlaxoSmithKline Protein Kinase Inhibitor Set Identifies an Inhibitor of Human Cytomegalovirus Replication that Prevents CREB and Histone H3 Post-Translational Modification. J Gen Virol 2017;Epub ahead of print:doi:10.1099/jgv.0.000713.
Nelms B, Dalomba NF, Lencer W. A targeted RNAi screen identifies factors affecting diverse stages of receptor-mediated transcytosis. J Cell Biol 2017;216(2):511-525.
Beelontally R, Wilkie GS, Lau B, Goodmaker CJ, Ho CMK, Swanson CM, Deng X, Wang J, Gray NS, Davison AJ, Strang BL. Identification of compounds with anti-human cytomegalovirus activity that inhibit production of IE2 proteins. Antiviral Res 2017;138:61-70.

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