Publications

2018
Zeid R, Lawlor MA, Poon E, Reyes JM, Fulciniti M, Lopez MA, Scott TG, Nabet B, Erb MA, Winter GE, Jacobson Z, Polaski DR, Karlin KL, Hirsch RA, Munshi NP, Westbrook TF, Chesler L, Lin CY, Bradner JE. Enhancer invasion shapes MYCN-dependent transcriptional amplification in neuroblastoma. Nat Genet. 2018;Jan 29 doi: 10.1038/s41588-018-0044-9.
Ouchida AT, Li Y, Geng J, Najafov A, Ofengeim D, Sun X, Yu Q, Yuan J. Synergistic effect of a novel autophagy inhibitor and Quizartinib enhances cancer cell death. Cell Death Dis. 2018;9(2):138.
2017
Hafner M, Niepel M, Subramanian K, Sorger PK. Designing drug response experiments and quantifying their results . Curr Protoc Chem Biol 2017;9(2):96-116.
Niepel M, Hafner M, Chung M, Sorger PK. Measuring cancer drug sensitivity and resistance in cultured cells . Curr Protoc Chem Biol 2017;9(2):55-74.
Abrial M, Paffett-Lugassy N, Jeffrey S, Jordan D, O'Laughlin E, Frederick CJ, Burns CG, Burns CE. TGF-β Signaling Is Necessary and Sufficient for Pharyngeal Arch Artery Angioblast Formation. Cell Rep 2017;20(4):973-983.
Zheng H, Colvin CJ, Johnson BK, Kirchhoff PD, Wilson M, Jorgensen-Muga K, Larsen SD, Abramovitch RB. Inhibitors of Mycobacterium tuberculosis DosRST signaling and persistence. Nat Chem Biol 2017;13(2):218-225.
Coulson GB, Johnson BK, Zheng H, Colvin CJ, Fillinger RJ, Haiderer ER, Hammer ND, Abramovitch RB. Targeting Mycobacterium tuberculosis Sensitivity to Thiol Stress at Acidic pH Kills the Bacteriumand Potentiates Antibiotics. Cell Chem Biol 2017;24(8):993-1004.
Fu B, Zhao M, Wang L, Patil G, Smith JA, Juncadella IJ, Zuvela-Jelaska L, Dorf ME, Li S. RNAi Screen and Proteomics Reveal NXF1 as a Novel Regulator of IRF5 Signaling. Sci Rep 2017;Jun 2; 7(1):2683.
Strang BL. RO0504985 is an inhibitor of CMGC kinase proteins and has anti-human cytomegalovirus activity [Internet]. Antiviral Res 2017;144:21-26. Publisher's Version
Maura D, Drees SL, Bandyopadhaya A, Kitao T, Negri M, Starkey M, Lesic B, Milot S, Deziel E, Zahler R, Pucci M, Felici A, Fetzner S, Lepine F, Rahme LG. Polypharmacology Approaches against the Pseudomonas aeruginosa MvfR Regulon and Their Application in Blocking Virulence and Antibiotic Tolerance. ACS Chem Bio 2017;:[Epub ahead of print].
Simpson KJ, Smith JA. Knocking down the obstacles to functional genomics data sharing. Sci Data 2017;4:170019 doi:10.1038/sdata.2017.19.
Khan AS, Murray MJ, Ho CM, Zuercher WJ, Reeves MB, Strang BL. High Throughput Screening of a GlaxoSmithKline Protein Kinase Inhibitor Set Identifies an Inhibitor of Human Cytomegalovirus Replication that Prevents CREB and Histone H3 Post-Translational Modification. J Gen Virol 2017;Epub ahead of print:doi:10.1099/jgv.0.000713.
Nelms B, Dalomba NF, Lencer W. A targeted RNAi screen identifies factors affecting diverse stages of receptor-mediated transcytosis. J Cell Biol 2017;216(2):511-525.
Beelontally R, Wilkie GS, Lau B, Goodmaker CJ, Ho CMK, Swanson CM, Deng X, Wang J, Gray NS, Davison AJ, Strang BL. Identification of compounds with anti-human cytomegalovirus activity that inhibit production of IE2 proteins. Antiviral Res 2017;138:61-70.
2016
Bird GH, Mazzola E, Opoku-Nsiah K, Lammert MA, Godes M, Neuberg DS, Walensky LD. Biophysical Determinants for Cellular Uptake of HydrocarbonStapled Peptide Helices. Nat Chem Biol 2016;12(10):845-52.
Chiaraviglio L, Kang YS, Kirby JE. High Throughput, Real-time, Dual-readout testing of intracellular antimicrobial activity and eukaryotic cell cytotoxicity. J Vis Exp 2016;117:doi: 10.3791/54841.
de Wispelaere M, Carocci M, Liang Y, Liu Q, Sun E, Vetter ML, Wang J, Gray NS, Yang PL. Discovery of host-targeted covalent inhibitors of dengue virus. Antiviral Res 2016;139:171-179.
Balasubramanian A, Manzano M, Teramoto T, Pilankatta R, Padmanabhan R. High-throughput screening for the identification of small-molecule inhibitors of the flaviviral protease. Antiviral Res 2016;134:6-16.

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