Publications

2017
Simpson KJ, Smith JA. Knocking down the obstacles to functional genomics data sharing. Sci Data 2017;4:170019 doi:10.1038/sdata.2017.19.
Khan AS, Murray MJ, Ho CM, Zuercher WJ, Reeves MB, Strang BL. High Throughput Screening of a GlaxoSmithKline Protein Kinase Inhibitor Set Identifies an Inhibitor of Human Cytomegalovirus Replication that Prevents CREB and Histone H3 Post-Translational Modification. J Gen Virol 2017;Epub ahead of print:doi:10.1099/jgv.0.000713.
Nelms B, Dalomba NF, Lencer W. A targeted RNAi screen identifies factors affecting diverse stages of receptor-mediated transcytosis. J Cell Biol 2017;
Beelontally R, Wilkie GS, Lau B, Goodmaker CJ, Ho CMK, Swanson CM, Deng X, Wang J, Gray NS, Davison AJ, Strang BL. Identification of compounds with anti-human cytomegalovirus activity that inhibit production of IE2 proteins. Antiviral Res 2017;138:61-70.
2016
Bird GH, Mazzola E, Opoku-Nsiah K, Lammert MA, Godes M, Neuberg DS, Walensky LD. Biophysical Determinants for Cellular Uptake of HydrocarbonStapled Peptide Helices. Nat Chem Biol 2016;12(10):845-52.
Chiaraviglio L, Kang YS, Kirby JE. High Throughput, Real-time, Dual-readout testing of intracellular antimicrobial activity and eukaryotic cell cytotoxicity. J Vis Exp 2016;117:doi: 10.3791/54841.
de Wispelaere M, Carocci M, Liang Y, Liu Q, Sun E, Vetter ML, Wang J, Gray NS, Yang PL. Discovery of host-targeted covalent inhibitors of dengue virus. Antiviral Res 2016;139:171-179.
Balasubramanian A, Manzano M, Teramoto T, Pilankatta R, Padmanabhan R. High-throughput screening for the identification of small-molecule inhibitors of the flaviviral protease. Antiviral Res 2016;134:6-16.
Baell J. Feeling Nature's PAINS: Natural Products, Natural Product Drugs, and Pan Assay Interference Compounds (PAINS). J Nat Prod 2016;79(3):616-628.
Polachek WS, Moshrif HF, Franti M, Coen DM, Streenu VB, Strang BL. High-Throughput Small Interfering RNA Screening Identifies Phosphatidylinositol 3-Kinase Class II Alpha as Important for Production of Human Cytomegalovirus Virions. J Virol 2016;90(18):8360-71.
Savidis G, McDougall WM, Meraner P, Perreira JM, Portmann JM, Trinucci G, John SP, Aker AM, Renzette N, Robbins DR, Guo Z, Green S, Kowalik TF, Brass AL. Identification of Zika Virus and Dengue Virus Dependency Factors using Functional Genomics. Cell Reports 2016;16(1):232-46.
Helenius IT, Nair A, Bittar HE, Sznaider JI, Sporn PH, Beitel GJ. Focused Screening Identifies Evoxine as a Small Molecule That Counteracts CO2-Induced Immune Suppression. J Biomol Screen 2016;21(4):363-71.
SBGrid Consortium. The SBGrid Consortium provides access to a variety of computing resources, including structures of ICCB-Longwood compounds for virtual screening. 2016;
Zervantonakis IK, Arvanitis CD. Controlled drug release and chemotherapy response in a novel acoustofluidic 3D tumor platform. Small 2016;12(19):2616-26.
Clark MJ, Miduturu C, Schmidt AG, Zhu X, Pitts JD, Wang J, Zhang J, Wojciechowski A, Chu JJ-H, Potisopon S, Gray NS, Yang PL. GNF-2 inhibits dengue virus by targeting Abl Kinases and the viral E protein. Cell Chemical Biology 2016;23(4):443-52.
Nishikawa JL, Boeszoermenyi A, Vale-Silva LA, Torelli R, Posteraro B, Sohn YJ, Ji F, Gelev V, Sanglard D, Sanguinetti M, Sadreyev RI, Mukherjee G, Bhyravabhotla J, Buhrlage SJ, Gray NS, Wagner G, Naar AM, Arthanari H. Inhibiting fungal multidrug resistance by disrupting an activator-mediator interaction. Nature 2016;530(7591):485-9.
Clark MJ, Midituru C, Schmidt AG, Zhu X, Pitts JD, Wang J, Potisopon S, Zhang J, Wojciechowski A, Chu JJH, Gray NS, Yang PL. GNF-2 Inhibits Dengue Virus by Targeting ABI Kinases and the Viral E Protein. Cell Chem Biol 2016;23(4):443-52.
Carocci M, Yang PL. Lactimidomycin is a broad-spectrum inhibitor of dengue and other RNA viruses. Antiviral Res 2016;128:57-62.

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