Publications
Acknowledgement of ICCB-L in Publications
Researchers using the services of ICCB-L staff or equipment agree to acknowledge the support of 'ICCB-Longwood Screening Facility at Harvard Medical School' in publications arising from your use of the facility. If an ICCB-L member has made an important intellectual contribution to the project, as determined by generally accepted criteria for academic collaborations, then that person should be considered for authorship on the publication. If your project was supported by a grant that also directly supports the ICCB-L, please consult the ICCB-L Director regarding the appropriate grant citation. Please notify Jen Smith upon public release of your publication.
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589 results
2024
[United States -- Massachusetts]: Harvard University; 2024. p. 135+.
[United States -- Massachusetts]: Harvard University; 2024. p. 135+.
Lanthanides are critical elements used in numerous modern technologies, but their mining and purification pose significant environmental challenges. This thesis describes the development of synthetic biology tools to enable more sustainable extraction of...
2024;151(13):dev202476+.
2024;151(13):dev202476+.
Generation of hematopoietic stem and progenitor cells (HSPCs) ex vivo and in vivo, especially the generation of safe therapeutic HSPCs, still remains inefficient. In this study, we have identified compound BF170 hydrochloride as a previously unreported...
Developmental Cell. Elsevier; 2024;59(23):3106–3123.e12,.
Developmental Cell. Elsevier; 2024;59(23):3106–3123.e12,.
2023
Du T, Song Y, Ray A, Wan X, Yao, Samur M, Shen C, Penailillo J, Sewastianik T, Tai YT, Fulciniti, Munshi N, Wu, Carrasco R, Chauhan D, Anderson K. Ubiquitin receptor PSMD4/Rpn10 is a novel therapeutic target in multiple myeloma.
Blood. 2023;(Jan 11).
Du T, Song Y, Ray A, Wan X, Yao, Samur M, Shen C, Penailillo J, Sewastianik T, Tai YT, Fulciniti, Munshi N, Wu, Carrasco R, Chauhan D, Anderson K. Ubiquitin receptor PSMD4/Rpn10 is a novel therapeutic target in multiple myeloma.
Blood. 2023;(Jan 11).
Ryan C, Brander D, Barr P, Tyekucheva S, Hackett L, Collins M, Fernandes S, Ren Y, Zhou Y, McDonough M, Walker H, McEwan M, Abramson J, Jacobsen E, LaCasce A, Fisher D, Brown J, Davids M. A phase 1b study of ibrutinib in combination with obinutuzumab in patients with relapsed or refractory chronic lymphocytic leukemia.
Leukemia. 2023;(Jan 30).
Ryan C, Brander D, Barr P, Tyekucheva S, Hackett L, Collins M, Fernandes S, Ren Y, Zhou Y, McDonough M, Walker H, McEwan M, Abramson J, Jacobsen E, LaCasce A, Fisher D, Brown J, Davids M. A phase 1b study of ibrutinib in combination with obinutuzumab in patients with relapsed or refractory chronic lymphocytic leukemia.
Leukemia. 2023;(Jan 30).
Chew K, Lee, Ozonoff A, Smith J, Levy O, Dowling D, Haren S. A protocol for high-throughput screening for immunomodulatory compounds using human primary cells.
STAR Protoc. 2023;4(3):102405.
Chew K, Lee, Ozonoff A, Smith J, Levy O, Dowling D, Haren S. A protocol for high-throughput screening for immunomodulatory compounds using human primary cells.
STAR Protoc. 2023;4(3):102405.
Yang JH, Petty C, Dixon-McDougall T, Lopez M, Tyshkovskiy A, Maybury-Lewis S, Tian X, Ibrahim N, Chen Z, Griffin P, Arnold M, Li J, Martinez O, Behn A, Rogers-Hammond R, Angeli S, Gladyshev V, Sinclair D. Chemically induced reprogramming to reverse cellular aging.
2023;15(13):5966–5989.
Yang JH, Petty C, Dixon-McDougall T, Lopez M, Tyshkovskiy A, Maybury-Lewis S, Tian X, Ibrahim N, Chen Z, Griffin P, Arnold M, Li J, Martinez O, Behn A, Rogers-Hammond R, Angeli S, Gladyshev V, Sinclair D. Chemically induced reprogramming to reverse cellular aging.
2023;15(13):5966–5989.
Ralvenius W, Mungenast A, Woolf H, Huston M, Gillingham T, Godin S, Penney J, Cam H, Gao F, Fernandez C, Czako B, Lightfoot Y, Ray W, Beckmann A, Goate A, Marcora E, Romero-Molina C, Ayata P, Schaefer A, Gjoneska E, Tsai LH. A novel molecular class that recruits HDAC/MECP2 complexes to PU.1 motifs reduces neuroinflammation.
J Exp Med. 2023;220(11):e20222105.
Ralvenius W, Mungenast A, Woolf H, Huston M, Gillingham T, Godin S, Penney J, Cam H, Gao F, Fernandez C, Czako B, Lightfoot Y, Ray W, Beckmann A, Goate A, Marcora E, Romero-Molina C, Ayata P, Schaefer A, Gjoneska E, Tsai LH. A novel molecular class that recruits HDAC/MECP2 complexes to PU.1 motifs reduces neuroinflammation.
J Exp Med. 2023;220(11):e20222105.
Quek R, Hardy K, Walker S, Nguyen D, Magalhães T, Salic, Gopalakrishnan S, Silver P, Mitchison T. Screen for Modulation of Nucleocapsid Protein Condensation Identifies Small Molecules with Anti-Coronavirus Activity.
ACS Chem Biol. 2023;18(3):583–594.
Quek R, Hardy K, Walker S, Nguyen D, Magalhães T, Salic, Gopalakrishnan S, Silver P, Mitchison T. Screen for Modulation of Nucleocapsid Protein Condensation Identifies Small Molecules with Anti-Coronavirus Activity.
ACS Chem Biol. 2023;18(3):583–594.
Park D, Nguyen S, Isenhart R, Shah P, Kim W, Barnett R, Chandra A, Luppino J, Harke J, Wai M, Walsh P, Abdill R, Yang R, Lan Y, Yoon S, Yunker R, Kanemaki M, Vahedi G, Phillips-Cremins J, Jain R, Joyce E. High-throughput Oligopaint screen identifies druggable 3D genome regulators.
Nature. 2023;620:209–217.
Park D, Nguyen S, Isenhart R, Shah P, Kim W, Barnett R, Chandra A, Luppino J, Harke J, Wai M, Walsh P, Abdill R, Yang R, Lan Y, Yoon S, Yunker R, Kanemaki M, Vahedi G, Phillips-Cremins J, Jain R, Joyce E. High-throughput Oligopaint screen identifies druggable 3D genome regulators.
Nature. 2023;620:209–217.
Sabag-Daigle A, Boulanger E, Thirugnanasambantham P, Law J, Bogard A, Behrman E, Gopalan V, Ahmer B. Identification of Small-Molecule Inhibitors of the Salmonella FraB Deglycase Using a Live-Cell Assay.
Microbiol Spectr. 2023;11(2):e0460622.
Sabag-Daigle A, Boulanger E, Thirugnanasambantham P, Law J, Bogard A, Behrman E, Gopalan V, Ahmer B. Identification of Small-Molecule Inhibitors of the Salmonella FraB Deglycase Using a Live-Cell Assay.
Microbiol Spectr. 2023;11(2):e0460622.
Sadeeshkumar H, Balaji A, Sutherland A, Mootien, Anthony K, Breaker R. Screening for small molecule inhibitors of SAH nucleosidase using an SAH riboswitch.
Anal Biochem. 2023;666:115047.
Sadeeshkumar H, Balaji A, Sutherland A, Mootien, Anthony K, Breaker R. Screening for small molecule inhibitors of SAH nucleosidase using an SAH riboswitch.
Anal Biochem. 2023;666:115047.