This library is available from Enzo Life Sciences and jointly purchased by ICCB-L and the Assay Development and Screening Facility (Children’s Hospital Boston) in August 2017 and plated in October 2017.
| Number of Compounds | 470 |
| Plate Numbers | 3854-3855 (2 Plates) |
| Concentration Information |
Variable from 5 mg/ml (~13 mM) down to 0.1 mM based upon potency and availability. Please refer to Screensaver for specific compound concentration. |
384-well Plate Format
Biomol ICCB-L Known Bioactives 2017 is based on the ICCB-Longwood Bioactives 1 collection (PL-0684-0685). This collection is nearly identical to the compounds that were in previous iterations of this library: plates 1361-1362, plates 1791-1792, plates 1989-1990 (4 compound difference) and plates 3402-3403 (10 compound difference). It was originally assembled by BIOMOL, working together with ICCB-Longwood, to provide a library of compounds that affect a wide variety of biological pathways relevant to ICCB-Longwood screening projects. The collection includes many classes of compounds including ion channel blockers, GPCR ligands, second messenger modulators, nuclear receptor ligands, actin and tubulin ligands, kinase inhibitors, protease inhibitors, gene regulation agents, lipid biosynthesis inhibitors, as well as other well-characterized compounds that perturb cell pathways. Because the compounds are plated at a high concentration, we suggest these 2 plates are not the first ones screened when an assay is initiated at ICCB-L.
For additional vendor-provided information, including potential targets/activities, please see Study 100010 in Screensaver.
Allison Costa - Sales Specialist
(631) 694-7070 Ext. 1338
acosta@enzo.com
http://www.enzolifesciences.com/
