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Human Microbiota Extracts 6 - Clardy Lab

Members of  Dr. Jon Clardy’s laboratory (Harvard Medical School) have assembled a library of partially purified extracts from members of the human microbiota: Bilophila wadsworthia, Clostridium bolteae, Clostridium clostridioforme, Clostridium innocuum, Clostridium symbiosum, Eubacterium hallii, Eubacterium rectale, Flavonifractor plautii, Gordonibacter urolithinfaciens, Klebsiella pneumoniaea, Ruminococcus lactaris, and Subdoligranulum variabile. There are multiple extracts per bacterium. The extracts have been partially purified to remove compounds of high polarity. This library was plated and added to the ICCB-Longwood collection in March 2024.

Number of Compounds 110
Plate Numbers 5235 (1 Plate)
Concentration Information 10 mg/mL in DMSO

384-well Plate Format

  • Plate 5235

Screening positives that have been confirmed by follow-up experiments on cherry picked samples can be further fractionated via a collaboration with the lab of Dr. Jon Clardy (Harvard Medical School). Please contact Jennifer Smith to arrange for purification of “hit” compounds from extract samples.

This library requires permission before screening. ICCB-Longwood screeners interested in screening this library should contact Jennifer Smith for more details.