Human Microbiota Extracts 5 - Clardy Lab

Members of  Dr. Jon Clardy’s laboratory (Harvard Medical School) have assembled a library of partially purified extracts from members of the human microbiota: Acinetobacter baumannii, Bacteroides fragilis, Bacteroides uniformis, Bifidobacterium bifidum, Bifidobacterium breve, Collinsella aerofaciens, Eggerthella lenta, Enterococcus faecalis, Faecalibacterium prausnitzii, Fusobacterium nucleatum, Klebsiella pneumoniae, Morganella morganii, Muribaculum intestinale, Oscillibacter sp., Staphylococcus aureus, Streptococcus infantis, Streptococcus mitis, Streptococcus oralis, Streptococcus pneumoniae, Streptococcus pyogenes, Streptococcus salivarius, Turicibacter sanguinis, and Veillonella parvulaThere are multiple extracts per bacteriumThe extracts have been partially purified to remove compounds of high polarity. This library was plated and added to the ICCB-Longwood collection in May 2023.

Number of Compounds 229
Plate Numbers 5078 (1 Plate)
Concentration Information Varied mg/mL in DMSO

384-well Plate Format

Screening positives that have been confirmed by follow-up experiments on cherry picked samples can be further fractionated via a collaboration with the lab of Dr. Jon Clardy (Harvard Medical School). Please contact Jennifer Smith to arrange for purification of “hit” compounds from extract samples.

This library requires permission before screening. ICCB-Longwood screeners interested in screening this library should contact Jennifer Smith for more details.