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ICCB-Longwood Meeting Notices
Other ICCB-L Notices
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ICCB-Longwood Investigator Initiated Screening
ICCB-Longwood is located at Harvard Medical School, 250 Longwood Avenue, Seeley Mudd Room 604, Boston MA 02115. For maps and directions, please click here.
The ICCB-Longwood Investigator Initiated Screening Program assists academic researchers in carrying out
high-throughput screens of chemical and RNAi libraries to identify new tools
for biological research. The ICCB-Longwood screening facility is built
around modular work stations, and assays are generally carried
out in 384-well plates. The ICCB-Longwood compound collection is continuously
growing, and over 150,000 compounds are currently available for
screening. Whole human genome and whole mouse genome siRNA libraries are also available for screening. The facility employs a staff-assisted screening model,
in which investigators using the facility are provided with access
to compound and siRNA libraries, and training in the use of some instruments,
such as liquid handling equipment,
plate readers, and screening microscopes. Staff members run all
complex automation for screens.
The ICCB-Longwood screening effort is expanded through close interactions with two other Harvard Medical School-affiliated programs, the National Screening Laboratory for the Regional Centers of Excellence in Biodefense and Emerging Infectious Disease (NSRB) and the Laboratory for Drug Discovery (LDDN). Together, these three screening efforts focus on broadly different areas, but all share the goal of using high throughput screening to further understand a variety of biological processes. Many resources, including compound and siRNA libraries, are shared among the three groups, with each providing support in its particular area of expertise.
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