Functional Genomics

Bibliographic References tagged with Functional Genomics

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Chong SJF, Lu J, Valentin R, Lehmberg TZ, Eu JQ, Wang J, Zhu F, Kong LR, Fernandes SM, Zhang J, Herbaux C, Goh BC, Brown JR, Niemann CU, Huber W, Zenz T, Davids MS. BCL-2 dependence is a favorable predictive marker of response to therapy for chronic lymphocytic leukemia.
Molecular cancer. 2025;24(1):62. PMID: 40025512
Chong SJF, Lu J, Valentin R, Lehmberg TZ, Eu JQ, Wang J, Zhu F, Kong LR, Fernandes SM, Zhang J, Herbaux C, Goh BC, Brown JR, Niemann CU, Huber W, Zenz T, Davids MS. BCL-2 dependence is a favorable predictive marker of response to therapy for chronic lymphocytic leukemia.
Molecular cancer. 2025;24(1):62. PMID: 40025512
Li W, Sparks RP, Sun C, Yang Y, Pantano L, Kirchner R, Arghiani N, Weilheimer A, Toles BJ, Chen JY, Moran SP, Barrera V, Li Z, Zhou P, Brassil ML, Wrobel D, Sui SJH, Aspnes G, Schuler M, Smith J, Medoff BD, Zhou C, Boustany-Kari CM, Rippmann JF, Santos DM, Doerner JF, Mullen AC. Screening the human druggable genome identifies ABHD17B as an anti-fibrotic target in hepatic stellate cells.
Nature communications. 2025;16(1):2109. PMID: 40025044
Li W, Sparks RP, Sun C, Yang Y, Pantano L, Kirchner R, Arghiani N, Weilheimer A, Toles BJ, Chen JY, Moran SP, Barrera V, Li Z, Zhou P, Brassil ML, Wrobel D, Sui SJH, Aspnes G, Schuler M, Smith J, Medoff BD, Zhou C, Boustany-Kari CM, Rippmann JF, Santos DM, Doerner JF, Mullen AC. Screening the human druggable genome identifies ABHD17B as an anti-fibrotic target in hepatic stellate cells.
Nature communications. 2025;16(1):2109. PMID: 40025044
Chang KC, Silvestri F, Oliphant MUJ, Martinez-Gakidis A, Orgill DP, Garber JE, Dillon DD, Brugge JS. Breast organoid suspension cultures maintain long-term estrogen receptor expression and responsiveness.
NPJ breast cancer. 2024;10(1):107. PMID: 39702422
Chang KC, Silvestri F, Oliphant MUJ, Martinez-Gakidis A, Orgill DP, Garber JE, Dillon DD, Brugge JS. Breast organoid suspension cultures maintain long-term estrogen receptor expression and responsiveness.
NPJ breast cancer. 2024;10(1):107. PMID: 39702422
Kilgas S, Syed A, Toolan-Kerr P, Swift ML, Roychoudhury S, Sarkar A, Wilkins S, Quigley M, Poetsch AR, Botuyan MV, Cui G, Mer G, Ule J, Drané P, Chowdhury D. NEAT1 modulates the TIRR/53BP1 complex to maintain genome integrity.
Nature communications. 2024;15(1):8438. PMID: 39349456
Kilgas S, Syed A, Toolan-Kerr P, Swift ML, Roychoudhury S, Sarkar A, Wilkins S, Quigley M, Poetsch AR, Botuyan MV, Cui G, Mer G, Ule J, Drané P, Chowdhury D. NEAT1 modulates the TIRR/53BP1 complex to maintain genome integrity.
Nature communications. 2024;15(1):8438. PMID: 39349456
Chidley C, Darnell A, Gaudio B, Lien E, Barbeau A, Vander-Heiden M, Sorger P. A CRISPRi/a screening platform to study cellular nutrient transport in diverse microenvironments.
Nat Cell Biol. 2024;(11 April).
Chidley C, Darnell A, Gaudio B, Lien E, Barbeau A, Vander-Heiden M, Sorger P. A CRISPRi/a screening platform to study cellular nutrient transport in diverse microenvironments.
Nat Cell Biol. 2024;(11 April).
Jovanović B, Temko D, Stevens L, Seehawer M, Fassl A, Murphy K, Anand J, Garza K, Gulvady A, Qiu X, Harper N, Daniels V, Xiao-Yun H, Ge J, Alečković M, Pyrdol J, Hinohara K, Egri S, Papanastasiou M, Vadhi R, Font-Tello A, Witwicki R, Peluffo G, Trinh A, Shu S, Diciaccio B, Ekram M, Subedee A, Herbert Z, Wucherpfennig K, Letai A, Jaffe J, Sicinski P, Brown M, Dillon D, Long H, Michor, Polyak K. Heterogeneity and transcriptional drivers of triple-negative breast cancer.
Cell Rep. 2023;42(12):113564.
Jovanović B, Temko D, Stevens L, Seehawer M, Fassl A, Murphy K, Anand J, Garza K, Gulvady A, Qiu X, Harper N, Daniels V, Xiao-Yun H, Ge J, Alečković M, Pyrdol J, Hinohara K, Egri S, Papanastasiou M, Vadhi R, Font-Tello A, Witwicki R, Peluffo G, Trinh A, Shu S, Diciaccio B, Ekram M, Subedee A, Herbert Z, Wucherpfennig K, Letai A, Jaffe J, Sicinski P, Brown M, Dillon D, Long H, Michor, Polyak K. Heterogeneity and transcriptional drivers of triple-negative breast cancer.
Cell Rep. 2023;42(12):113564.
Schmaier A, Anderson P, Chen S, El-Darzi E, Aivasovsky I, Kaushik M, Sack K, Hartzell H, Parikh S, Flaumenhaft, Schulman S. TMEM16E regulates endothelial cell procoagulant activity and thrombosis.
J Clin Invest. 2023;133(11):e163808.
Schmaier A, Anderson P, Chen S, El-Darzi E, Aivasovsky I, Kaushik M, Sack K, Hartzell H, Parikh S, Flaumenhaft, Schulman S. TMEM16E regulates endothelial cell procoagulant activity and thrombosis.
J Clin Invest. 2023;133(11):e163808.
Boekell K, Brown B, Talbot B, Schlondorff J. Trpc6 gain-of-function disease mutation enhances phosphatidylserine exposure in murine platelets.
PLoS One. 2022;17(6):e0270431.
Boekell K, Brown B, Talbot B, Schlondorff J. Trpc6 gain-of-function disease mutation enhances phosphatidylserine exposure in murine platelets.
PLoS One. 2022;17(6):e0270431.
Chen DY, Chin C, Kenney D, Tavares A, Khan N, Conway H, Liu G, Choudhary M, Gertje H, O’Connell A, Adams S, Kotton D, Herrmann A, Ensser A, Connor J, Bosmann M, Li J, Gack M, Baker S, Kirchdoerfer R, Kataria Y, Crossland N, Douam F, Saeed M. Spike and nsp6 are key determinants of SARS-CoV-2 Omicron BA.1 attenuation.
Nature. 2023;615:143–150.
Chen DY, Chin C, Kenney D, Tavares A, Khan N, Conway H, Liu G, Choudhary M, Gertje H, O’Connell A, Adams S, Kotton D, Herrmann A, Ensser A, Connor J, Bosmann M, Li J, Gack M, Baker S, Kirchdoerfer R, Kataria Y, Crossland N, Douam F, Saeed M. Spike and nsp6 are key determinants of SARS-CoV-2 Omicron BA.1 attenuation.
Nature. 2023;615:143–150.
Vora S, Fontana P, Mao T, Leger V, Zhang Y, Fu TM, Lieberman, Gehrke L, Shi M, Wang L, Iwasaki A, Wu. Targeting stem-loop 1 of the SARS-CoV-2 5’ UTR to suppress viral translation and Nsp1 evasion.
Proc Natl Acad Sci U S A. 2022;119(9):e2117198119.
Vora S, Fontana P, Mao T, Leger V, Zhang Y, Fu TM, Lieberman, Gehrke L, Shi M, Wang L, Iwasaki A, Wu. Targeting stem-loop 1 of the SARS-CoV-2 5’ UTR to suppress viral translation and Nsp1 evasion.
Proc Natl Acad Sci U S A. 2022;119(9):e2117198119.