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LINCS 4 - Kinase Inhibitor Library

This is a collection of characterized kinase inhibitors purchased from a variety of vendors and provided to ICCB-Longwood by HMS LINCS. Each compound is plated at 4 concentrations (10 mM, 2 mM, 0.4 mM and 0.08 mM). The concentrations of the compounds on this library plate are according to quadrant; Quadrant A1 is at 10mM, Quadrant A2 is at 2mM, Quadrant B1 is at 0.4mM and Quadrant B2 is at 0.08mM, please see map above for a visual layout.

Number of Compounds

169 (x 4 concentrations)

676 wells

Plate Numbers 3672-3674 (3 Plates)
Concentration Information 0.08mM, 0.4mM, 2mM, 10mM in DMSO

384-well Plate Format

  • Plates 3572-3673
  • Plate 3674
Note: Until 11.2.2017, the compound in plate #3673 wells I09, I10, J09 and J10 was incorrectly referenced as AP26113 in Screensaver and HMS LINCS DB. This is because multiple vendors had incorrectly referenced the compound as this through May 2016 and buyers were not notified when the error was fixed. This error is referenced in Clinical Cancer Research DOI: 10.1158/1078-0432.CCR-16-0569. It has now been corrected and is ALK-IN-1.
Please refer to the HMS LINCS website and HiTS Small Molecule Suite for more detailed information about the contents of this library.