Small-molecule GSDMD agonism in tumors stimulates antitumor immunity without toxicity

Publication information:

Fontana P, Du G, Zhang Y, Zhang H, Vora S, Hu J, Shi M, Tufan A, Healy L, Xia S, Lee DJ, Li Z, Baldominos P, Ru H, Luo H, Agudo J, Lieberman J, Wu H. Small-molecule GSDMD agonism in tumors stimulates antitumor immunity without toxicity.
Cell. 2024;187(22):6165–6181. PMID: 39243763