The US National Cancer Institute's (NCI) Natural Product Repository is one of the world's largest, most diverse collections of natural products. It contains over 230,000 unique extracts derived from plant, marine, and microbial organisms that have been collected from biodiverse regions throughout the world. This national resource is available to the research community for the screening of extracts and the isolation of bioactive natural products.
The NCI Program for Natural Product Discovery (NPNPD) is designed to advance natural product discovery technologies and facilitate the discovery of structurally defined, validated lead molecules ready for translation, specifically as it relates to cancer. NPNPD has created a prefractionated library from over 125,000 natural product extracts with the aim of producing a publicly-accessible, HTS-amenable library of >1,000,000 fractions. Over 300,000 of these fractions are available for screening at ICCB-Longwood, made possible with funding from the Ludwig Center at Harvard.
Hear about the Kaelin Lab's (DFCI) recent screening of this library and follow up collaboration with the NCI: https://www.youtube.com/watch?v=vgOkiJBQ5HA
| Number of Compounds | 326,656 |
| Plate Numbers | 4147-5074 (928 Plates) |
| Concentration Information | 2.5 mg/mL in DMSO |
384-well Plate Format
