Human Microbiota Extracts 2

Members of Dr. Jon Clardy’s laboratory (Harvard Medical School) assembled a library of partially purified extracts from members of the human microbiota: Bifidobacterium adolescentis, Bifidobacterium longum, Akkermansia muciniphila, Streptococcus thermophilus, Streptococcus mutans, Streptococcus sanguinis, Bacteroides fragilis and other human gut microbiome members. There are multiple extracts per bacterium. The extracts have been partially purified to remove compounds of high polarity. This library was plated and added to the ICCB-Longwood collection in January 2017.

Number of Compounds:
160
Plate Numbers:
3761 (1 Plate)
Concentration Information:
10 mg/mL in DMSO
Plate 3761
384-Well Plate Format

Screening positives that have been confirmed by follow-up experiments on cherry picked samples can be further fractionated via a collaboration with the lab of Dr. Jon Clardy (Harvard Medical School). Please contact Jennifer Smith to arrange for purification of “hit” compounds from extract samples.

This library requires permission before screening. ICCB-Longwood screeners interested in screening this library should contact Jennifer Smith for more details.