ChemBridge Focused Ion Channel Core

This is a focused collection that was jointly purchased by an NIH Center grant to Dr. Alan D’Andrea (DFCI) and the Assay Development and Screening Facility (Boston Children's Hospital) in December 2012 and plated in January 2013. It contains 250 compounds selected from ChemBridge’s larger IONCore Library, which is a computationally selected library of more than 4,000 small molecules selected from ChemBridge’s CORE Library. Compounds were selected using pharmacophores generated from known ion channel actives. There are 29 target-type combinations covered in this library by 21 different scaffolds, with most scaffolds having a minimum of 5 compounds.

Number of Compounds
250
Plate Numbers
3408 (1 Plate)
Concentration Information
10 mM in DMSO

384-well Plate Format

For specific scaffold information please see attached file.

The ChemBridge website contains additional information on the IONCore Library.

Ordering Compounds from ChemBridge:

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