This collection was purchased in Fall 2008 from BIOMOL (catalog #2840; www.enzolifesciences.com) and plated in Spring 2009. It is based on the ICCB-Longwood Bioactives 1 collection (PL-0684-0685). This collection is also identical to the compounds that were in the high concentration of plates 1361-1362 and plates 1791-1792. It was assembled by BIOMOL, working together with ICCB-Longwood, to provide a library of compounds that affect a wide variety of biological pathways relevant to ICCB-Longwood screening projects. The collection includes many classes of compounds including ion channel blockers, GPCR ligands, second messenger modulators, nuclear receptor ligands, actin and tubulin ligands, kinase inhibitors, protease inhibitors, gene regulation agents, lipid biosynthesis inhibitors, as well as other well-characterized compounds that perturb cell pathways.
This collection contains 41 FDA-approved drugs.
| Number of Compounds | 480 |
| Plate Numbers | 1989-1990 (2 Plates) |
| Concentration Information | Variable from 5 mg/ml (~13 mM) down to 0.1 mM based upon potency and availability, in DMSO |
The last copy of this library was retired in January 2013.
384-well Plate Format
