#  Fees 

 



A fee is charged for access to functional genomics screening at ICCB-Longwood. This fee helps us to recover a portion of our operating expenses. ICCB-Longwood screening fees (and associated Facilities and Administration fees) are revised annually based on the Harvard Fiscal Year (July 1 – June 30). The fee structure is updated on the ICCB-Longwood website as soon as it is available. All charges are based on the screening fee at the time of service, not a previously provided estimate or price structure from a previous fiscal year.

For screens originating from non-HMS Quad investigator labs (this includes HMS Affiliates whose labs are not located on the HMS Quadrangle and Non-Harvard investigators), the indicated F&A is added at each stage of the screening fee.

Fees below represent the rates for FY26 (July 1, 2025 - June 30, 2026).

Screening fees do not include the cost of assay reagents and consumables. Funding for all assay reagents and consumables (excluding library) is provided by the screener.



 

SortScreening Fee MilestonesAcademicIndustryF&ASet up

$6,336

$14,256

$1,268

Synthego Druggable sgRNA CRISPR library (29 plates)

$8,816

$19,836

$1,764

Full genome siRNA library (66 plates)

$20,063

$45,141

$4,013

Per library plate

$304

$684

$61

lncRNA siRNA library (7 plates)

$2,128

$4,788

$426

miRNA library (5 plates)

$1,520

$3,420

$304

GPCR, Ion Channel, Protease or Ubiquitin siRNA library (2 plates)

$608

$1,368

$122

 Kinase siRNA library (3 plates)

$912

$2,052

$183





Fees will begin to be charged once work is initiated at ICCB-Longwood.

The above fees for screening the full siRNA genome include cherry picks for the individual siRNA duplexes corresponding to 300 genes per screen (1200 duplexes for Dharmacon genome, 900 duplexes for an Ambion screen). Additional cherry picks can be requested at $4 per duplex picked / $16 per gene (academic pricing). The duplex volume provided is the same volume of SMARTpool reagents that were used in the primary screen.

The above full druggable sgRNA CRISPR fee includes a cherry pick of 150 sgRNAs for each screen.

It is possible for investigators to select whether they would like to screen the entire genome or instead screen focused siRNA libraries. For the human genome, this decision should be made prior to initiating the screen, as the most concise way to screen the entire genome is through utilizing the continuous human genome siRNA library. Custom siRNA library screening is also possible.

Interested investigators should contact [Jennifer Smith](mailto:jennifer_smith@hms.harvard.edu) for more details and/or to determine which rate applies to their screen.