Publications by Year: 2011

2011
Cotta-Ramusino C, 3rd ERMD, Hurov K, Sowa ME, Harper JW, Elledge SJ. A DNA damage response screen identifies RHINO, a 9-1-1 and TopBP1 interacting protein required for ATR signaling. Science 2011;332(6035):1313-7.
Sigoiloot FD, King RW. Vigilance and Validation: Keys to Success in RNAi Screening. ACS Chem Biol 2011;6(1):47-60.
Senapedis WT, Kennedy CJ, Boyle PM, Silver PA. Whole genome siRNA cell-based screen links mitochondria to Akt signaling network through uncoupling of electron transport chain. Mol Biol Cell 2011;22(10):1791-805.
Thorne CA, Lafleur B, Lewis M, Hanson AJ, Jernigan KK, Weaver DC, Huppert KA, Chen TW, Wiehaidit C, Cselenyi CS, Tahinci E, Meyers KC, Waskow E, Orton D, Salic A, Lee LA, Robbins DJ, Huppert SS, Lee E. A biochemical screen fro identification of small molecule regulators of the Wnt pathway using Xenopus egg extracts. J Biomol Screen 2011;16(9):995-1006.
Li X, Liu N, Zhang H, Knudson SE, Li HJ, Lai CT, Simmerling C, Slayden RA, Tonge PJ. CoA adducts of 4-oxo-4-phenylbut-2-enoates: inhibitors of MenB from the M. tuberculosis menaquinone biosynthesis pathway [Internet]. 2011; ACS Med Chem Lett 2(11):818-823

Data from this screen has been deposited in PubChem Bioassay. AID #540299

Huh JR, Leung MW, Huang P, Ryan DA, Krout MR, Malapaka RR, Chow J, Manel N, Ciofani M, Kim SV, Cuesta A, Santori FR, Lafaille JJ, Xu HE, Gin DY, Rastinejad F, Littman DR. Digoxin and its derivatives suppress TH17 cell differentiation by antagonizing RORγt activity [Internet]. 2011; Nature 472, 486-90
Kawahara G, Karpf JA, Myers JA, Alexander MS, Guyon JR, Kunkel LM. Drug screening in a zebrafish model of Duchenne muscular dystrophy [Internet]. 2011; Proc Natl Acad Sci U S A 108:5331-6.
Schulte J, Sepp KJ, Wu C, Hong P, Littleton JT. High-content chemical and RNAi screens for suppressors of neurotoxicity in a Huntington’s Disease model [Internet]. 2011; PLoS One 6(8): e23841
Geiss BJ, Stahla-Beek HJ, Hannah AM, Gari HH, Henderson BR, Saeedi BJ, Keenan SM. A high-throughput screening assay for the identification of flavivirus NS5 capping enzyme GTP-binding inhibitors: implications for antiviral drug development [Internet]. 2011; J Biomol Screen 16(8):852-61
Campagnola G, Gong P, Peersen OB. High-throughput screening identification of poliovirus RNA-dependent RNA polymerase inhibitors [Internet]. 2011; Antiviral Res 91(3):241-251

Data from this screen has been deposited in PubChem Bioassay. AID #588519

Faghiri Z, Santiago RB, Wu Z, Widmer G. High-throughput screening in suboptimal growth conditions identifies agonists of Giardia lamblia proliferation [Internet]. 2011; Parasitology Feb;138(2):194-200
Schormann N, Sommers CI, Prichard MN, Keith KA, Noah JW, Nuth M, Ricciardi RP, Chattopadhyay D. Identification of protein-protein interaction inhibitors targeting vaccinia virus processivity factor for developing antiviral agents [Internet]. 2011; Antimicrob Agents Chemother 55(11):5054-62.
Zhou Y, Rajabi H, Kufe D. Mucin 1 C-terminal subunit oncoprotein is a target for small-molecule inhibitors [Internet]. 2011; Mol Pharmacol 79(5):886-93.
Anthony KG, Strych U, Yeung KR, Shoen CS, Perez O, Krause KL, Cynamon MH, Aristoff PA, Koski RA. New classes of alanine racemase inhibitors identified by high-throughput screening show antimicrobial activity against Mycobacterium tuberculosis [Internet]. 2011; PLoS One 6(5):e20374
Greenberger S, Yuan S, Walsh LA, Boscolo E, Kang KT, Matthews B, Mulliken JB, Bischoff J. Rapamycin suppresses self-renewal and vasculogenic potential of stem cells isolated from infantile hemangioma [Internet]. 2011; J Invest Dermatol Dec;131(12):2467-76.
Gonsalves F, Klein K, Carson B, Katz S, Ekas L, Evans S, Nagourney R, Cardozo T, Brown AMC, Dasgupta R. An RNAi-based chemical genetic screen identifies three small-molecule inhibitors of the Wnt/wingless signaling pathway. Proc Natl Acad Sci USA 2011;108(15):5954-63.
Côté M, Misasi J, Ren T, Bruchez A, Lee K, Filone CM, Hensley L, Li Q, Ory D, Chandran K, Cunningham J. Small molecule inhibitors reveal Niemann-Pick C1 is essential for Ebola virus infection [Internet]. 2011; Nature 477(7364):344-8
Sun F, Zhou L, Zhao BC, Deng X, Cho H, Yi C, Jian X, Song CX, Luan CH, Bae T, Li Z, He C. Targeting MgrA-mediated virulence regulation in Staphylococcus aureus [Internet]. 2011; Chem Biol 18:1032-41.

Data from this screen has been deposited in PubChem Bioassay. AID #602314

Harris ES, Erickson SD, Tolopko AN, Cao S, Craycroft JA, Scholten R, Fu Y, Wang W, Liu Y, Zhao Z, Clardy J, Shamu CE, Eisenberg DM. Traditional Medicine Collection Tracking System (TM-CTS): a database for ethnobotanically driven drug-discovery programs. J Ethnopharmacol 2011;135(2):590-3.
Sigoillot FD, King RW. Vigilance and Validation: Keys to Success in RNAi Screening. ACS Chem Biol 2011;6(1):47-60.

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