Publications by Year: 2010

2010
Moore MJ, Wang Q, Kennedy CJ, Silver PA. An alternative splicing network links cell-cycle control to apoptosis. Cell 2010;142(4):625-36.
Lipinski MM, Zheng B, Lu T, Yan Z, Py BF, Ng A, Xavier RJ, Li C, Yankner BA, Scherzer CR, Yuan J. Genome-wide analysis reveals mechanisms modulating autophagy in normal brain aging and in Alzheimer’s disease. Proc Natl Acad Sci USA. 2010;107(32):14164-9.
Smith JA, White EA, Sowa ME, Powell MLC, Ottinger M, Harper JW, Howley PM. Genome-wide siRNA screen identifies SMCX, EP400, and Brd4 as E2-dependent regulators of human papillomavirus oncogene expression. Proc Natl Acad Sci USA. 2010;107(8):3752-7.
Yoon JC, Ng A, Kim BH, Bianco A, Xavier RJ, Elledge SJ. Wnt signaling regulates mitochondrial physiology and insulin sensitivity. Genes Dev 2010;24(14):1507-18.
Kwan P, Birmingham A. NoiseMaker: simulated screens for statistical assessment. Bioinformatics 2010;26(19):2484-5.
Paik EJ, de Jong JL, Pugach E, Opara P, Zon L. A chemical genetic screen in zebrafish for pathways interacting with cdx4 in primitive hematopoiesis [Internet]. http://www.ncbi.nlm.nih.gov/pubmed?cmd=Search&term=20415644%5BPMID%5D 2010; Zebrafish 7, 61-8
Lee K, Campbell J, Swoboda JG, Cuny GD, Walker S. Development of improved inhibitors of wall teichoic acid biosynthesis with potent activity against Staphylococcus aureus [Internet]. 2010; Bioorg Med Chem Lett 20(5):1767-70

Data from this screen has been deposited in PubChem Bioassay. AID #463173

Zhou S, Cerny AM, Bowen G, Chan M, Kurt-Jones EA, Finberg RW. Discovery of a novel TLR2 signaling inhibitor with anti-viral activity [Internet]. 2010; Antiviral Res 87(3):295-306
Lee BH, Lee MJ, Park S, Oh D-C, Elsasser S, Chen P-C, Gartner C, Dimova N, Hanna J, Gygi SP, Wilson SM, King RW, Finley D. Enhancement of Proteasome Activity by a Small-Molecule Inhibitor of Usp14 [Internet]. 2010; Nature. September 9; 467(7312):179-184.
Hoffman GR, Moerke NJ, Hsia M, Shamu CE, Blenis J. A high-throughput, cell-based screening method for siRNA and small molecule inhibitors of mTORC1 signaling using the In Cell Western technique. Assay Drug Dev Technol 2010;8(2):186-99.
Cai S, Lindo P, Park JB, Vasa K, Singh BR. The identification and biochemical characterization of drug-like compounds that inhibit botulinum neurotoxin serotype A endopeptidase activity [Internet]. 2010; Toxicon 55(4):818-26.
Harmon DE, Davis AJ, Castillo C, Mecsas J. Identification and characterization of small molecule inhibitors of Yop translocation in Yersinia pseudotuberculosis [Internet]. 2010; Antimicrob Agents Chemother 54(8):3241-54
Wahome PG, Bai Y, Neal LM, Robertus JD, Mantis NJ. Identification of small-molecule inhibitors of ricin and shiga toxin using a cell-based high-throughput screen [Internet]. 2010; Toxicon 56(3):313-23
Passer BJ, Cheema T, Zhou B, Wakimoto H, Zupa C, Razmjoo M, Sarte J, Wu S, Wu CL, Noah JW, Li Q, Buolamwini JK, Yen Y, Rabkin SD, Martuza RL. Identification of the ENT1 antagonists dipyridamole and dilazep as amplifiers of oncolytic herpes simplex virus-1 replication [Internet]. 2010; Cancer Res 70(10):3890-5
Lieberman LA, Higgins DE. Inhibition of Listeria monocytogenes infection by neurological drugs [Internet]. 2010; Int J Antimicrob Agents 35(3):292-296
Vasan M, Neres J, Williams J, Wilson DJ, Teitelbaum AM, Remmel RP, Aldrich CC. Inhibitors of the salicylate synthase (MbtI) from Mycobacterium tuberculosis discovered by high-throughput screening [Internet]. 2010; Chem Med Chem 5(12):2079-87

PubChem URL
Data from this screen has been deposited in PubChem Bioassay. AID #493033

Castoreno AB, Smurnyy Y, Torres AD, Vokes MS, Jones TR, Carpenter AE, Eggert US. Small molecules discovered in a pathway screen target the Rho pathway in cytokinesis [Internet]. 2010; Nat Chem Biol 6(6):457-63
Li X, Liu N, Zhang H, Knudson SE, Slayden RA, Tonge PJ. Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: Novel antibacterial agents against Mycobacterium tuberculosis [Internet]. 2010; Bioorg Med Chem Lett 20(21):6306-9

PubChem URL

Data from this screen has been deposited in PubChem Bioassay. AID #540299

Tolopko AN, Sullivan JP, Erickson SD, Wrobel D, Chiang SL, Rudnicki K, Rudnicki S, Nale J, Selfors LM, Greenhouse D, Muhlich JL, Shamu CE. Screensaver: an open source lab information management system (LIMS) for high throughput screening facilities. BMC Bioinformatics 2010;11:260.