Publications by Year: 2008

2008
Ohn T, Kedersha N, Hickman T, Tisdale S, Anderson P. A functional RNAi screen links O-GlcNAc modification of ribosomal proteins to stress granule and processing body assembly. Nat Cell Biol 2008;10(10):1224-31.
Hitomi J, Christofferson DE, Ng A, Degterev A, Xavier RJ, Yuan J. Identification of a molecular signaling network that regulates a cellular necrotic cell death pathway. Cell 2008;135(7):1311-23.
Simpson KJ, Selfors LM, Bui J, Reynolds A, Leake D, Khvorova A, Brugge JS. Identification of genes that regulate epithelial cell migration using an siRNA screening approach. Nat Cell Biol 2008;10(9):1027-38.
Brass AL, Dykxhoorn DM, Benita Y, Yan N, Engelman A, Xavier RJ, Lieberman J, Elledge SJ. Identification of host proteins required for HIV infection through a functional genomic screen. Science 2008;319(5865):921-6.
Krishnan MN, Ng A, Sukumaran B, Gilfoy FD, Uchil PD, Sultana H, Brass AL, Adametz R, Tsui M, Qian F, Montgomery RR, Lev S, Mason PW, Koski RA, Elledge SJ, Xavier RJ, Agaisse H, Fikrig E. RNA interference screen for human genes associated with West Nile virus infection. Nature 2008;455(7210):242-5.
Neres J, Wilson DJ, Celia L, Beck BJ, Aldrich CC. Aryl acid adenylating enzymes involved in siderophore biosynthesis: fluorescence polarization assay, ligand specificity, and discovery of non-nucleoside inhibitors via high-throughput screening [Internet]. 2008; Biochemistry 47(45):11735-49

PubChem URL
Data from this screen has been deposited in PubChem Bioassay. AID #485350

Cassidy-Stone A, Chipuk JE, Ingerman E, Song C, Yoo C, Kuwana T, Kurth MJ, Hinshaw JE, Green DR, Nunnari J. Chemical inhibition of the mitochondrial division dynamin reveals its role in bax/bak-dependent mitochondrial outer membrane permeabilization [Internet]. 2008; Dev Cell 14(2):193-204
Renlund N, Pieretti-Vanmarcke R, O’Neill FH, Zhang L, Donahoe PK, Teixeira J. c-Jun N-terminal kinase inhibitor II (SP600125) activates Mullerian inhibiting substance type II receptor-mediated signal transduction [Internet]. 2008; Endocrinology 149(1):108-15
Fleming J, Outeiro TF, Slack M, Lindquist SL, Bulawa CE. Detection of compounds that rescue Rab1-synuclein toxicity [Internet]. 2008; Methods Enzymol 2008;439:339-51
Huang J, Lesser CF, Lory S. The essential role of the CopN protein in Chlamydia pneumoniae intracellular growth [Internet]. 2008; Nature. 2008 Nov 6;456 (7218):112-5.
Krysan DJ, Didone L. A high-throughput screening assay for small molecules that disrupt yeast cell integrity [Internet]. 2008; J Biomol Screen 13(7):657-64.
Mueller NH, Pattabiraman N, Ansarah-Sobrinho C, Viswanathan P, Pierson TC, Padmanabhan R. Identification and biochemical characterization of small molecule inhibitors of West Nile Virus serine protease by a high throughput screen [Internet]. 2008; Antimicrob Agents Chemother 52(9):3385-93
Bonilla-Santiago R, Wu Z, Zhang L. Identification of growth inhibiting compounds in a Giardia lablia high-throughput screen [Internet]. 2008; Molec Biochem Parasitol 162(2):149-54
Ciustea M, Silverman JE, Shudofsky AMD, Ricciardi RP. Identification of Non-Nucleoside DNA Synthesis Inhibitors of Vaccinia Virus by High-Throughput Screening [Internet]. 2008; J Med Chem 51(20):6563-70

PubChem URL
Data from this screen has been deposited in PubChem Bioassay. AID #493162

Felise HB, Nguyen HV, Pfuetzner RA, Barry KC, Jackson SR, Blanc MP, Bronstein PA, Kline T, Miller SI. An inhibitor of gram-negative bacterial virulence protein secretion [Internet]. 2008; Cell Host Microbe 4 (4):325-36
Hoffmann HH, Palese P, Shaw ML. Modulation of influenza virus replication by alteration of sodium ion transport and protein kinase C activity [Internet]. 2008; Antiviral Res 80(2):124-34
Komazin-Meredith G, Santos WL, Filman DJ, Hogle JM, Verdine GL, Coen DM. The positively charged surface of herpes simplex virus UL42 mediates DNA binding [Internet]. 2008; J Biol Chem Mar 7;283(10):6154-61
Hwang YC, Chu JJ, Yang PL, Chen W, Yates MV. Rapid identification of inhibitors that interfere with poliovirus replication using a cell-based assay [Internet]. 2008; Antiviral Res 77(3):232-6
Stirrett KL, Ferreras JA, Jayaprakash V, Sinha BN, Ren T, Quadri LE. Small molecules with structural similarities to siderophores as novel antimicrobials against Mycobacterium tuberculosis and Yersinia pestis [Internet]. 2008; Bioorg Med Chem Lett 18(8):2662-8
Zimmer M, Ebert BL, Neil C, Brenner K, Papaioannou I, Melas A, Tolliday N, Lamb J, Pantopoulos K, Golub T, Iliopoulos O. Small-molecule inhibitors of HIF-2a translation link its 5’UTR iron-responsive element to oxygen sensing [Internet]. 2008; Mol Cell 32(6):838-48

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