#  LDDN-CNS 

 



This library of 320 compounds was provided to ICCB-Longwood by the [Laboratory for Drug Discovery in Neurodegeneration](https://www.bwhneurosciences.org/lddn/) at Brigham and Women's Hospital (Dr Kevin Hodgetts) in December 2017. The compounds in the library include: (i) 160 novel compounds with central nervous system (CNS) drug cores and physicochemical properties suitable for blood brain barrier penetration (e.g., cLogP 1-4, PSA 40-80, MW&lt;400, HBD&lt;3); and (ii) 160 compounds with known CNS activity and mechanism of action.

SortNumber of Compounds:

320

Plate Numbers:

3760 (1 Plate) 

Concentration Information:

10 mM in DMSO





 ![Plate 3760](/sites/g/files/omnuum5406/files/iccb/files/plate_3760_lddn.png)

 

384-Well Plate Format

 

This library requires permission before screening. ICCB-Longwood screeners interested in screening this library should contact [Jennifer Smith](mailto:jennifer_smith@hms.harvard.edu) for more details.