#  Asinex 2 

 



This Asinex Macrocyclic Library was jointly purchased by the [Blavatnik Biomedical Accelerator](http://otd.harvard.edu/accelerators/blavatnik-biomedical-accelerator/) and Priscilla Yang (Harvard Medical School, NIH Center of Excellence for Translational Research grant) and plated in Summer 2017. As stated on the [Asinex website](http://www.asinex.com/libraries-macrocyclic-5-html/), their chemists elaborated a library of diverse macrocycles using an effective tool box of synthetic methods including solid phase-supported synthesis, RCM, click-chemistry, and ring expansion, generating novel macrocyclic scaffolds that are diverse and medchem relevant. Macrocycles tend to be larger than traditional screening molecules, enabling them to function as discovery tools for targets with shallow or extended binding sites. Due to their restricted conformational flexibility accompanied by a favorable orientation of peripheral substituents, many macrocycles effectively mimic the ɑ-helical or β-hairpin topology of biologically relevant proteins. The Asinex Macrocyclic Library provides a source of peptidomimetics.

Note: There are 1,245 duplicated compounds as a consequence of how Asinex plated this library.

SortNumber of Compounds:

23,031

Plate Numbers:

3769-3840 (72 Plates)

Concentration Information:

10mM in DMSO





 ![Plates 3769-3839](/sites/g/files/omnuum5406/files/iccb/files/website_library_384_plate_3769-3839.png)

 

384-Well Plate Format ![Plate 3840](/sites/g/files/omnuum5406/files/iccb/files/plate_3840.png)

 

384-Well Plate Format

 

 **Compound order information:**

 Mark Parisi - Executive Director  
ASINEX Corporation  
101 N. Chestnut St. Suite 104  
Winston-Salem, NC 27101

 Tel: 1-877-ASINEX1 (toll free)  
E-mail: [MParisi@asinex-usa.com](mailto:///MParisi@asinex-usa.com)