| Technology - Screening Facility |
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The ICCB-Longwood Screening Facility, located in SGM 613 and 610, provides
small molecule libraries and equipment for high-throughput screening
of chemical libraries, and it also develops HTS technology. The
screening facility has the following equipment and resources available
for use by investigators:
- Robotics for pin transfer of compounds from library stock
plates to assay plates.
- Plate readers with luminescence, fluorescence, fluorescence
polarization, time-resolved fluorescence, and absorbance detection
capability.
- Screening microscopes that image wells from 96- and 384-well
assay plates.
- Automated plate washers.
- Liquid handling robots for filling assay plates.
- Tissue culture hoods and incubators.
- Multichannel pipettes.
- Plate Sealer and Bar Code Labeler
An outline of the guidelines for waste disposal at the ICCBL can be found here (pdf)
Click below to learn more about specific instrumentation used
at the ICCB-Longwood
Pin
Transfer of Compounds to Assay Plates
RNAi Transfection
Liquid
Handling - rapid plate dispenser
Liquid Handling - automated pipettors
Plate
Readers
Q-PCR
Screening by Imaging
Hit Picker
(for "cherry picking")
Other Technology
Tissue
Culture Area
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