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ICBG Fungal Extracts 2

Number of extracts	460
Plate Numbers	1559-1560 (2 Plates)
Concentration Information	Dried extracts resuspended at ~15 mg/ml in DMSO
Plate Format	384-well plate Plate 1559: Column 23-24 (empty) Click plate image to enlarge Plate 1560: Column 1,3,5,7,9,11,13,15,17,19,21 [B,D,F,H,J,L,N,P] (empty) Column 2,4,6,8,10,12,14,16,18,20 [B,D,E-P] (empty) Column 22 [B-P] (empty) Column 23-24 (empty) Click plate image to enlarge

This library was plated and added to the collection in April 2005. Production of this fungal extract library was funded by an International Cooperative Biodiversity Groups (ICBG) grant from the NIH to Dr. Jon Clardy. The library contains partially purified extracts from endophytic fungi (fungi that live in higher plants) that grow in Costa Rica. Crude extracts from the fungi were obtained and further fractionated to eliminate nuisance compounds, especially those of high molecular weight or high polarity.

Screening positives that have been confirmed by follow-up experiments on cherry picked samples can be further fractionated via a collaboration with the lab of Dr. Jon Clardy (Harvard Medical School). Please contact Caroline Shamu (caroline_shamu@hms.harvard.edu) to arrange for purification of "hit" compounds from extract samples.