Application for Small Molecule Screening
 
Instructions

ICCB-Longwood welcomes applications from Harvard Medical School (HMS), Harvard Hospital-affiliated investigators. Applications must be submitted each time a new screen is proposed. We are currently accepting applications on a rolling basis. If the facility becomes oversubscribed we will institute a waiting list.

Note that, as of October 1, 2005, a fee is charged for access to small molecule screening at ICCB-Longwood. This fee helps us to recover some of our operating costs. It is revised annually on a schedule based on the Harvard fiscal year (July 1 - June 30), thus updates to the fee structure are generally posted here in the late summer. Please contact Caroline Shamu with questions regarding fee revisions.

For HMS Quadrangle-based investigators, the small molecule screening fee is $4600 per screen. For all other investigators, the fee is about $1000 higher, to cover facilities and administration costs assessed by HMS. The fee is in addition to the cost of assay reagents and supplies provided by the screener. The fee will be charged only once screening is underway and not during the development phase of the screen. Please contact Caroline Shamu if you have any questions.

Before screening, you will also need to agree to the ICCB-Longwood protocol and data sharing policies outlined in the ICCB-Longwood Data Sharing Agreement. We must have a signed Data Sharing Agreement for each collaborator before use of the Screening Facility is scheduled. If possible, please submit the signed Agreement at the same time as the completed Application.
(Download Data Sharing Agreement (PDF))

For more information about working at ICCB-Longwood to carry out small molecule screening projects, please see our website, http://iccb.med.harvard.edu. Note that we do our best not to initiate collaborations that compete with existing ones. Therefore, we avoid situations in which two different groups are carrying out substantially similar screens on the same compound collections at the same time. The decision as to whether a proposed screen will compete with ongoing assays is made by the ICCB-Longwood Screen Review Committee in consultation with the investigators involved. Precedence is generally given to the screen first proposed and to those proposed by ICCB-Longwood members.

Often, investigators request a Letter of Collaboration for grants intended to fund a screen. Please understand that we can only write such a letter if we know that we can accommodate your screen. Therefore, please try to submit your Application to screen at the ICCB-Longwood well in advance of grant deadlines, and please warn us if you expect to need a Letter of Collaboration.

Please send any questions about the ICCB-Longwood Screening Application or evaluation process to screeniccb_apply"AT"hms.harvard.edu.

If you think you are having problems submitting an Application via this website, please send an explanatory email directly to screeniccb_apply@hms.harvard.edu or to the Director of ICCB-Longwood. Thank you.