Publications by Year: 2016

2016
Verreault M, Schmitt C, Goldwirt L, Pelton K, Haidar S, Levasseur C, Guehennec J, Knoff D, Labussière M, Marie Y, Ligon AH, Mokhtari K, Hoang-Xuan K, Sanson M, Alexander BM, Wen PY, Delattre J-Y, Ligon KL, Idbaih A. Preclinical Efficacy of the MDM2 Inhibitor RG7112 in MDM2-Amplified and TP53 Wild-type Glioblastomas [Internet]. Clin Cancer Res 2016;22(5):1185–1196. Publisher's Version
Russo BC, Stamm LM, Raaben M, Kim CM, Kahoud E, Robinson LR, Bose S, Queiroz AL, Herrera BB, Baxt LA, Mor-Vaknin N, Fu Y, Molina G, Markovitz DM, Whelan SP, Goldberg MB. Intermediate filaments enable pathogen docking to trigger type 3 effector translocation [Internet]. Nat Microbiol 2016;1:16025. Publisher's Version
Moerke N, Fallahi-Sichani M. Reverse Phase Protein Arrays for Compound Profiling [Internet]. Curr Protoc Chem Biol 2016;8(3):179-196. Publisher's Version
Baldridge RD, Rapoport TA. Autoubiquitination of the Hrd1 Ligase Triggers Protein Retrotranslocation in ERAD [Internet]. Cell 2016;166(2):394-407. Publisher's Version
Kuznetsova A, Yu Y, Hollister-Lock J, Opare-Addo L, Rozzo A, Sadagurski M, Norquay L, Reed JE, Khattabi IE, Bonner-Weir S, Weir GC, Sharma A, White MF. Trimeprazine increases IRS2 in human islets and promotes pancreatic β cell growth and function in mice [Internet]. JCI Insight 2016;1(3):e80749. Publisher's Version
Pasquina L, Santa-Maria JP, Wood BM, Moussa SH, Matano LM, Santiago M, Martin SES, Lee W, Meredith TC, Walker S. A synthetic lethal approach for compound and target identification in Staphylococcus aureus [Internet]. Nat Chem Biol 2016;12(1):40-45. Publisher's Version
Ramm S, Adler M, Vaidya VS. A High-Throughput Screening Assay to Identify Kidney Toxic Compounds [Internet]. Curr Protoc Toxicol 2016;69 Publisher's Version
Costello DA, Villareal VA, Yang PL. Desmosterol Increases Lipid Bilayer Fluidity during Hepatitis C Virus Infection [Internet]. ACS Infect Dis 2016;2(11):852-862. Publisher's Version
Li J, Shin S, Sun Y, Yoon S-O, Li C, Zhang E, Yu J, Zhang J, Blenis J. mTORC1-Driven Tumor Cells Are Highly Sensitive to Therapeutic Targeting by Antagonists of Oxidative Stress [Internet]. Cancer Res 2016;76(16):4816–4827. Publisher's Version
Matano LM, Morris HG, Wood BM, Meredith TC, Walker S. Accelerating the discovery of antibacterial compounds using pathway-directed whole cell screening [Internet]. Bioorg Med Chem 2016;24(24):6307-6314. Publisher's Version
Fuchs B, Rajamuthiah R, Souza AC, Eatemadpour S, Rossoni RD, Santos DA, Junqueira JC, Rice LB, Mylonakis E. Inhibition of bacterial and fungal pathogens by the orphaned drug auranofin. Future Med Chem 2016;8(2):117-132.
Barrow JJ, Balsa E, Verdeguer F, Tavares CD, Soustek MS, 4th LRH, Jedrychowski M, Vogel R, Paulo JA, Smeitinik J, Gygi SP, Doench J, Root DE, Puigserver P. Bromodomain Inhibitors Correct Bioenergetic Deficiency Caused by Mitochondrial Disease Complex I Mutations. Mol Cell 2016;64(1):163-175.
Bird GH, Mazzola E, Opoku-Nsiah K, Lammert MA, Godes M, Neuberg DS, Walensky LD. Biophysical Determinants for Cellular Uptake of HydrocarbonStapled Peptide Helices. Nat Chem Biol 2016;12(10):845-52.
Chiaraviglio L, Kang YS, Kirby JE. High Throughput, Real-time, Dual-readout testing of intracellular antimicrobial activity and eukaryotic cell cytotoxicity. J Vis Exp 2016;117:doi: 10.3791/54841.
de Wispelaere M, Carocci M, Liang Y, Liu Q, Sun E, Vetter ML, Wang J, Gray NS, Yang PL. Discovery of host-targeted covalent inhibitors of dengue virus. Antiviral Res 2016;139:171-179.
Balasubramanian A, Manzano M, Teramoto T, Pilankatta R, Padmanabhan R. High-throughput screening for the identification of small-molecule inhibitors of the flaviviral protease. Antiviral Res 2016;134:6-16.
Baell J. Feeling Nature's PAINS: Natural Products, Natural Product Drugs, and Pan Assay Interference Compounds (PAINS). J Nat Prod 2016;79(3):616-628.
Polachek WS, Moshrif HF, Franti M, Coen DM, Streenu VB, Strang BL. High-Throughput Small Interfering RNA Screening Identifies Phosphatidylinositol 3-Kinase Class II Alpha as Important for Production of Human Cytomegalovirus Virions. J Virol 2016;90(18):8360-71.
Savidis G, McDougall WM, Meraner P, Perreira JM, Portmann JM, Trinucci G, John SP, Aker AM, Renzette N, Robbins DR, Guo Z, Green S, Kowalik TF, Brass AL. Identification of Zika Virus and Dengue Virus Dependency Factors using Functional Genomics. Cell Reports 2016;16(1):232-46.
Helenius IT, Nair A, Bittar HE, Sznaider JI, Sporn PH, Beitel GJ. Focused Screening Identifies Evoxine as a Small Molecule That Counteracts CO2-Induced Immune Suppression. J Biomol Screen 2016;21(4):363-71.

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