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Publications by Year: 2013

2013
Davis BJ, Erlanson DA. Learning from our mistakes: the 'unknown knowns' in fragment screening. Bioorg Med Chem Lett 2013;23(10):2844-52.
Hutz JE, Nelson T, Wu H, McAllister G, Moutsatsos I, Jaeger SA, Bandyopadhyay S, Nigsch F, Cornett B, Jenkins JL, Selinger DW. The multidimensional perturbation value: a single metric to measure similarity and activity of treatments in high-throughput multidimensional screens. J Biomol Screen 2013;18(4):367-77.
Cryan LM, Habeshian KA, Caldwell TP, Morris MT, Ackroyd PC, Christensen KA, Rogers MS. Identification of small molecules that inhibit the interaction of TEM8 with anthrax protective antigen using a FRET assay. J Biomol Screen 2013;18(6):714-25.
Cryan LM, Bazinet L, Habeshian KA, Cao S, Clardy J, Christensen KA, Rogers MS. 1,2,3,4,6-Penta-O-galloyl-β-D-glucopyranose inhibits angiogenesis via inhibition of capillary morphogenesis gene 2. J Med Chem 2013;56(5):1940-5.
Romero D, Sanabria-Valentín E, Vlamakis H, Kolter R. Biofilm inhibitors that target amyloid proteins [Internet]. 2013; Chem Biol 20(1):102-10.
Sulli C, Banik SS, Schilling J, Moer A, Xiang X, Payne R, Wanless A, Willis SH, Paes C, Rucker JB, Doranz BJ. Detection of proton movement directly across viral membranes to identify novel influenza virus M2 Inhibitors [Internet]. 2013; J Virol. Oct;87(19):10679-86.
Tang Y, Xie T, Florian S, Moerke N, Shamu C, Benes C, Mitchison TJ. Differential determinants of cancer cell insensitivity to antimitotic drugs discriminated by a one-step cell imaging assay [Internet]. 2013; J Biomol Screen Oct;18(9):1062-71.
Chen C, Wonsey DR, Lemieux ME, Kung AL. Differential disruption of EWS-FLI1 binding by DNA-binding agents [Internet]. 2013; PLoS One Jul 22;8(7):e69714.
Bai H, Chen T, Ming J, Sun H, Cao P, Fusco DN, Chung RT, Chorev M, Jin Q, Aktas BH. Dual Activators of Protein Kinase R (PKR) and Protein Kinase R-Like Kinase (PERK) Identify Common and Divergent Catalytic Targets [Internet]. 2013; Chembiochem. 14(10):1255-62.
Escande C, Nin V, Price NL, Capellini V, Gomes AP, Barbosa MT, O’Neil L, White TA, Sinclair DA, Chini EN. Flavonoid apigenin is an inhibitor of the NAD+ ase CD38: implications for cellular NAD+ metabolism, protein acetylation, and treatment of metabolic syndrome. Diabetes 2013;62(4):1084-93.
Christensen QH, Grove TL, Booker SJ, Greenberg EP. A high-throughput screen for quorum-sensing inhibitors that target acyl-homoserine lactone synthases. Proc Natl Acad Sci USA 2013;110(34):13815-20.

PubChem URL Data from this screen has been deposited in PubChem Bioassay. AID #720554

Cryan LM, Habeshian KA, Caldwell TP, Morris MT, Ackroyd PC, Christensen KA, Rogers MS. Identification of small molecules that inhibit the interaction of TEM8 with anthrax protective antigen using a FRET assay. J Biomol Screen 2013;18(6):714-25.
Lee K, Ren T, Côté M, Gholamreza B, Misasi J, Bruchez A, Cunningham J. Inhibition of Ebola virus infection: identification of Niemann-Pick C1 as the target by optimization of a chemical probe. ACS Med Chem Lett 2013;4(2):239-243.
Lee Y, Mootien S, Shoen C, Destefano M, Cirillo P, Asojo OA, Yeung KR, Ledizet M, Cynamon MH, Aristoff PA, Koski RA, Kaplan PA, Anthony KG. Inhibition of mycobacterial alanine racemase activity and growth by thiadiazolidinones [Internet]. 2013; Biochem Pharmacol. Jul 15;86(2):222-30.
Le X, Pugach EK, Hettmer S, Storer NY, Liu J, Wills AA, DiBiase A, Chen EY, Ignatius MS, Poss KD, Wagers AJ, Langenau DM, Zon L. A novel chemical screening strategy in zebrafish identifies common pathways in embryogenesis and rhabdomyosarcoma development [Internet]. 2013; Development (Cambridge, England) 140, 2354-64
Chamoun-Emanuelli AM, Pecheur EI, Simeon RL, Huang D, Cremers PS, Chen Z. Phenothiazines inhibit hepatitis C virus entry, likely by increasing the fluidity of cholesterol-rich membranes [Internet]. 2013; Antimicrob Agents Chemother. Jun;57(6):2571-81.
Lafleur MD, Sun L, Lister I, Keating J, Nantel A, Long L, Ghannoum M, North J, Lee RE, Coleman K, Dahl T, Lewis K. Potention of azole antifungals by 2-adamantanamine [Internet]. 2013; Antimicrob Agents Chemother Aug;57(8):3585-92.
Kirienko NV, Kirienko DR, Larkins-Ford J, Wählby C, Ruvkun G, Ausubel FM. Pseudomonas aeruginosa Disrupts Caenorhabditis elegans Iron Homeostasis, Causing a Hypoxic Response and Death [Internet]. 2013; Cell host & microbe 13, 406-16.

Data from this screen has been deposited in PubChem Bioassay. AID #651566

Chen C, Shanmugasundaram K, Rigby AC, Kung AL. Shikonin, a natural product from the root of Lithospermum erythrorhizon, is a cytotoxic DNA-binding agent [Internet]. 2013; Eur J Pharm Sci Apr 11;49(1):18-26.
Lu L, Hannoush RN, Goess BC, Varadarajan S, Shair MD, Kirchhausen T. The small molecule dispergo tubulates the endoplasmic reticulum and inhibits export [Internet]. 2013; Molecular biology of the cell 24, 1020-9.

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